Metal- and solvent-free synthesis of aniline- and phenol-based triarylmethanes<i>via</i>Brönsted acidic ionic liquid catalyzed Friedel-Crafts reaction
Nipaphorn Ponpao, Warapong Senapak, Rungnapha Saeeng, Jaray Jaratjaroonphong, Uthaiwan Sirion
Abstract
]. This protocol was successfully performed under metal- and solvent-free conditions with a broad range of substrates, giving the corresponding aniline-based triarylmethane products in good to excellent yields (up to 99%). In addition, alternative aromatic nucleophiles such as phenols and electron-rich arenes were also studied using this useful approach to achieve a diversity of triarylmethane derivatives in high to excellent yields.
Topics & Concepts
Friedel–Crafts reactionIonic liquidAnilineCatalysisChemistryPhenolSolventMetalOrganic chemistryBrønsted–Lowry acid–base theoryInorganic chemistrySynthesis of Indole DerivativesChemical Synthesis and ReactionsIonic liquids properties and applications