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Type 2 cytokines in the thymus activate Sirpα+ dendritic cells to promote clonal deletion

Elise R. Breed, Matouš Vobořil, K. Maude Ashby, Ryan J. Martinez, Lily J. Qian, Haiguang Wang, Oscar Camilo Salgado, Christine H. O’Connor, Kristin A. Hogquist

2022Nature Immunology51 citationsDOIOpen Access PDF

Topics & Concepts

BiologyClonal deletionImmunologyCentral toleranceCell biologyAntigen-presenting cellImmune systemT cellCytokineDendritic cellAntigenMajor histocompatibility complexAntigen presentationT-cell receptorImmunotherapy and Immune ResponsesT-cell and B-cell ImmunologyImmune Cell Function and Interaction
Type 2 cytokines in the thymus activate Sirpα+ dendritic cells to promote clonal deletion | Litcius