In the wake of the pandemic: Preparing for Long COVID
Selina Rajan, Kamlesh Khunti, Nisreen A Alwan, Claire J. Steves, Nathalie MacDermott, Alisha Morsella, Ester Angulo, Juliane Winkelmann, Lucie Bryndová, Inês Fronteira, Coralie Gandré, Zeynep Or, Sophie Gerkens, Anna Sagan, Juliana de Oliveira Miranda Simões, Walter Ricciardi, Antonio Giulio de Belvis, Andrea Silenzi, Enrique Bernal‐Delgado, Francisco Estupiñán‐Romero, Michael McKee
Abstract
COVID-19 can cause persistent ill-health. Around a quarter of people who have had the virus experience symptoms that continue for at least a month but one in 10 are still unwell after 12 weeks. This has been described by patient groups as “Long COVID”.<br/>Our understanding of how to diagnose and manage Long COVID is still evolving but the condition can be very debilitating. It is associated with a range of overlapping symptoms including generalized chest and muscle pain, fatigue, shortness of breath, and cognitive dysfunction, and the mechanisms involved affect multiple system and include persisting inflammation, thrombosis, and autoimmunity. It can affect anyone, but women and health care workers seem to be at greater risk.<br/>Long COVID has a serious impact on people’s ability to go back to work or have a social life. It affects their mental health and may have significant economic consequences for them, their families and for society.<br/>Policy responses need to take account of the complexity of Long COVID and how what is known about it is evolving rapidly