p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators
Charles N. Birts, Arindam Banerjee, Matthew Darley, Charles R. Dunlop, Sarah J. Nelson, Sharandip K. Nijjar, Rachel Parker, Jonathan West, Ali Tavassoli, Matthew Rose‐Zerilli, Jeremy P. Blaydes
Abstract
ratio enables cells to avoid cellular damage caused by mismatches between metabolic supply and demand.
Topics & Concepts
GlycolysisAnaerobic glycolysisCell biologyCancer cellCancerChemistryBiologyRegulatorCancer researchBiochemistryMetabolismGeneGeneticsKruppel-like factors researchEpigenetics and DNA MethylationCancer-related gene regulation