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Programmable synthesis of difluorinated hydrocarbons from alkenes through a photocatalytic linchpin strategy

Zhi‐Qi Zhang, Cheng‐Qiang Wang, Longji Li, Jared L. Piper, Zhi-Hui Peng, Jun‐An Ma, Fa‐Guang Zhang, Jie Wu

2023Chemical Science34 citationsDOIOpen Access PDF

Abstract

-linked derivatives of complex drugs and natural products. This method opens up new avenues for the synthesis of structurally diverse difluorinated hydrocarbons and highlights the utility of ligated boryl radicals in organofluorine chemistry.

Topics & Concepts

ChemistryCombinatorial chemistryReagentHalogenRadicalOrganic chemistryAlkylFluorine in Organic ChemistryRadical Photochemical ReactionsInorganic Fluorides and Related Compounds
Programmable synthesis of difluorinated hydrocarbons from alkenes through a photocatalytic linchpin strategy | Litcius