Evaluation of antiviral activity of<i>Carica papaya</i>leaves against SARS-CoV-2 assisted by metabolomic profiling
Amr Adel, Mohamed S. Elnaggar, Amgad Albohy, Ahmed A. El‐Rashedy, Ahmed Mostafa, Omnia Kutkat, Usama Ramadan Abdelmohsen, Eman Al‐Sayed, Mohamed A. Rabeh
Abstract
The n -hexane extract showed a significant antiviral activity. In addition, annotated compounds exhibited high binding scores on 6 target viral proteins in silico .
Topics & Concepts
CaricaMetabolomicsSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)VirologyProfiling (computer programming)2019-20 coronavirus outbreakBiologyTraditional medicineChemistryComputational biologyBotanyMedicineBioinformaticsInfectious disease (medical specialty)Computer sciencePathologyDiseaseOutbreakOperating systemPapaya Research and ApplicationsMedicinal Plant ResearchNanoparticles: synthesis and applications