Intranasal administration of exosomes derived from adipose mesenchymal stem cells ameliorates depressive-like behaviors and inhibits inflammation via AMPK/mTOR-mediated autophagy
Siqi Sun, Jingtong Rong, Chao Wang, Ruiling Li, Honghan Zhang, Wei Wang, Hao Duan, Zhaowen Nie, Dan Xiang, Zhongchun Liu
Topics & Concepts
AutophagyAMPKMicrovesiclesNasal administrationMesenchymal stem cellAdipose tissuePI3K/AKT/mTOR pathwayInflammationExosomeMedicineCancer researchCell biologymicroRNAChemistryPharmacologySignal transductionEndocrinologyInternal medicineBiologyApoptosisPhosphorylationProtein kinase ABiochemistryGeneTryptophan and brain disordersAutophagy in Disease and TherapyMesenchymal stem cell research