MicroRNAs in cardiovascular disease
Gerasimos Siasos, Evanthia Bletsa, Panagiota K. Stampouloglou, Evangelos Oikonomou, Vasiliki Tsigkou, Stavroula Α. Paschou, Konstantinos Vlasis, Georgios Marinos, Manolis Vavuranakis, Christodoulos Stefanadis, Dimitris Tousoulis
Abstract
Cardiovascular disease (CVD) remains the predominant cause of human morbidity and mortality in developed countries. Currently, microRNAs have been investigated in many diseases as well-promising biomarkers for diagnosis, prognosis, and disease monitoring. Plenty studies have been designed so as to elucidate the properties of microRNAs in the classification and risk stratification of patients with CVD and also to evaluate their potentials in individualized management and guide treatment decisions. Therefore, in this review article, we aimed to present the most recent data concerning the role of microRNAs as potential novel biomarkers for cardiovascular disease.