Ferroptosis promotes microtubule-associated protein tau aggregation via GSK-3β activation and proteasome inhibition
Shaohui Wang, Yao Jiang, Yabo Liu, Qianhui Liu, Hongwei Sun, Mengjie Mei, Xiaomei Liao
Topics & Concepts
GSK-3HyperphosphorylationTau proteinProteasomeCell biologyMicrotubuleProgrammed cell deathChemistryIntracellularProtein aggregationLipid peroxidationKinaseBiochemistryBiologyNeuroscienceOxidative stressApoptosisAlzheimer's diseaseMedicineInternal medicineDiseaseFerroptosis and cancer prognosisAlzheimer's disease research and treatmentsMitochondrial Function and Pathology