Pharmacotranscriptomic profiling of resistant triple-negative breast cancer cells treated with lapatinib and berberine shows upregulation of PI3K/Akt signaling under cytotoxic stress
Parham Jabbarzadeh Kaboli, Shuang Luo, Yao Chen, Masume Jomhori, Saber İmani, Shixin Xiang, Zhigui Wu, Mingxing Li, Jing Shen, Yueshui Zhao, Xu Wu, Chi Hin Cho, Zhangang Xiao
Topics & Concepts
LapatinibProtein kinase BCancer researchBiologyPI3K/AKT/mTOR pathwayBreast cancerTriple-negative breast cancerDownregulation and upregulationCancerSignal transductionCell biologyBiochemistryTrastuzumabGeneticsGeneBerberine and alkaloids researchLung Cancer Treatments and MutationsPI3K/AKT/mTOR signaling in cancer