Silencing of long non-coding RNA CRNDE promotes autophagy and alleviates neonatal hypoxic-ischemic brain damage in rats
Chunhua Fu, Fangfang Lai, Sai Chen, Caixia Yan, Binghong Zhang, Chengzhi Fang, Gao-Hua Wang
Topics & Concepts
AutophagyGene silencingTUNEL assayBrain damageSmall hairpin RNANeuroprotectionApoptosisViability assayProgrammed cell deathRNA interferenceBiologySmall interfering RNAPharmacologyCell cultureTransfectionRNANeuroscienceGene knockdownBiochemistryGeneticsGeneAutophagy in Disease and TherapyCancer-related molecular mechanisms researchHeme Oxygenase-1 and Carbon Monoxide