Eco-friendly synthesis of a porous reduced graphene oxide–polypyrrole–gold nanoparticle hybrid nanocomposite for electrochemical detection of methotrexate using a strip sensor
Reshmi A. Sukumaran, Kavitha Lakavath, V. V. N. Phanikumar, Sampath Karingula, Kuldeep Mahato, K. Yugender Goud
Abstract
. This combination highlights its exceptional performance in detecting analytes with high precision and sensitivity. The sensor exhibited a long-term continuous monitoring stability response to monitor the MTX drug in human serum for 4 hours. The sensor's high sensitivity, selectivity, reproducibility, and stability over time emphasize its potential as a valuable tool for the swift on-site testing of anticancer drugs in clinical and environmental settings.
Topics & Concepts
PolypyrroleGrapheneMaterials scienceNanocompositeNanotechnologyNanoparticleOxideElectrochemistryChemistryComposite materialElectrodePolymerMetallurgyPolymerizationPhysical chemistryElectrochemical sensors and biosensorsConducting polymers and applicationsAdvanced Nanomaterials in Catalysis