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Identification of novel xanthine oxidase inhibitors via virtual screening with enhanced characterization of molybdopterin binding groups

Lu Zhang, Jin‐Ying Tian, Hanzeng Cheng, Yajun Yang, Ying Yang, Fei Ye, Zhiyan Xiao

2022European Journal of Medicinal Chemistry14 citationsDOIOpen Access PDF

Topics & Concepts

PharmacophoreChemistryVirtual screeningXanthine oxidaseQuantitative structure–activity relationshipDocking (animal)StereochemistryCombinatorial chemistryHyperuricemiaHydrogen bondMoleculeBiochemistryUric acidEnzymeOrganic chemistryNursingMedicineGout, Hyperuricemia, Uric AcidPeptidase Inhibition and AnalysisBiochemical and Molecular Research
Identification of novel xanthine oxidase inhibitors via virtual screening with enhanced characterization of molybdopterin binding groups | Litcius