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Commensal epitopes drive differentiation of colonic T <sub>regs</sub>

Michal Kuczma, Edyta Szurek, Anna Cebula, Benoît Chassaing, Yu‐Jin Jung, Sang‐Moo Kang, James G. Fox, Bärbel Stecher, Leszek Ignatowicz

2020Science Advances76 citationsDOIOpen Access PDF

Abstract

Colonic commensal-derived antigens support expansion and differentiation of immunosupressive CD4 T cells.

Topics & Concepts

EpitopeAntigenBiologyImmune systemFOXP3ImmunologyInflammationMicrobiomeAkkermansia muciniphilaT cellMicrobiologyGut floraGeneticsImmune Cell Function and InteractionEscherichia coli research studiesT-cell and B-cell Immunology
Commensal epitopes drive differentiation of colonic T <sub>regs</sub> | Litcius