A thermo-responsive supramolecular hydrogel that senses cholera toxin <i>via</i> color-changing response
Dipen Biswakarma, Nilanjan Dey, Santanu Bhattacharya
Abstract
A Pyrene-based amphiphile with C4-alkanoyl spacer and lactose (PyLac) self-assembles in the aqueous media to form an injectable hydrogel. It shows preferential binding with Cholera Toxin (CT) via its terminal galactose residue, and hence can be employed for the selective detection of CT via color-changing response.
Topics & Concepts
Cholera toxinSupramolecular chemistryChemistryToxinBiophysicsNanotechnologyMaterials scienceMicrobiologyMoleculeBiochemistryBiologyOrganic chemistrySupramolecular Self-Assembly in MaterialsPolydiacetylene-based materials and applicationsLuminescence and Fluorescent Materials