Tumor and blood B-cell abundance outperforms established immune checkpoint blockade response prediction signatures in head and neck cancer
Tiangen Chang, Aris Spathis, Alejandro A. Schäffer, N. Gavrielatou, Fengshen Kuo, Dongya Jia, Sumit Mukherjee, Cem Sievers, P. Economopoulou, M Anastasiou, Myrto Moutafi, Lipika R. Pal, Joris L. Vos, Andrew S. Lee, Sophia Lam, Kai Zhao, Peng Jiang, Clint Allen, Periklis Foukas, Georgia Gomatou, Grégoire Altan‐Bonnet, Luc G.T. Morris, Amanda Psyrri, Eytan Ruppin
Topics & Concepts
MedicineBlockadeHead and neck cancerImmune checkpointCancerHead and neckOncologyImmune systemAbundance (ecology)Internal medicineImmunologySurgeryReceptorEcologyBiologyCancer Immunotherapy and BiomarkersHead and Neck Cancer StudiesSingle-cell and spatial transcriptomics