Flexible Fitting of PROTAC Concentration–Response Curves with Changepoint Gaussian Processes
Elizaveta Semenova, Maria Luisa Guerriero, Bairu Zhang, Andreas Hock, Philip Hopcroft, Ganesh Kadamur, Avid M. Afzal, Stanley E. Lazic
Topics & Concepts
Sigmoid functionGaussianComputer scienceReproducibilityRanking (information retrieval)AlgorithmStatisticsBiological systemMathematicsData miningChemistryArtificial intelligenceComputational chemistryArtificial neural networkBiologyProtein Degradation and InhibitorsViral Infectious Diseases and Gene Expression in InsectsReceptor Mechanisms and Signaling