High HPK1+PD-1+TIM-3+CD8+ T cells infiltration predicts poor prognosis to immunotherapy in NSCLC patients
Jingxin Zhang, Ziyuan Ren, Yun Hu, Shijie Shang, Ruiyang Wang, Jiachun Ma, Zengfu Zhang, Meng Wu, Fei Wang, Jinming Yu, Dawei Chen
Topics & Concepts
Granzyme BImmunotherapyGranzymeCD8Cytotoxic T cellTumor microenvironmentPD-L1MedicineT cellImmunologyImmune systemCancer researchInternal medicineOncologyBiologyPerforinIn vitroBiochemistryCancer Immunotherapy and BiomarkersCAR-T cell therapy researchImmunotherapy and Immune Responses