A Closer Look at the Cellular and Molecular Components of the Deep/Muscular Fasciae
Caterina Fede, Carmelo Pirri, Chenglei Fan, Lucía Petrelli, Diego Guidolin, Raffaele De, Carla Stecco
Abstract
The fascia can be defined as a dynamic highly complex connective tissue network composed of different types of cells embedded in the extracellular matrix and nervous fibers: each component plays a specific role in the fascial system changing and responding to stimuli in different ways. This review intends to discuss the various components of the fascia and their specific roles; this will be carried out in the effort to shed light on the mechanisms by which they affect the entire network and all body systems. A clear understanding of fascial anatomy from a microscopic viewpoint can further elucidate its physiological and pathological characteristics and facilitate the identification of appropriate treatment strategies.