Fluorometric discrimination of tyrosine isomers based on the inner filter effect of chiral Au nanoparticles on MoS<sub>2</sub> quantum dots
Qianqian Zhao, Datong Wu, Zheng‐Zhi Yin, Wenrong Cai, Haifeng Zhou, Yong Kong
Abstract
A fluorescent chiral sensor is proposed based on the inner filter effect (IFE) of chiral Au nanoparticles (AuNPs) on MoS2 quantum dots (MoS2 QDs), which can be used for the discrimination of the isomers of tyrosine (Tyr). l-Tyrosine (l-Tyr) can induce obvious agglomeration of the chiral AuNPs, leading to an attenuated IFE of the chiral AuNPs and greatly restored fluorescence of the MoS2 QDs, and thus the enantioselective recognition of the Tyr isomers can be achieved. Also, l-Tyr but not d-Tyr induced agglomeration of the chiral AuNPs is confirmed by the larger association constant between l-Tyr and the chiral sensor.
Topics & Concepts
Quantum dotNanoparticleChemistryFilter (signal processing)NanotechnologyMaterials scienceComputer scienceComputer visionAdvanced biosensing and bioanalysis techniquesNanocluster Synthesis and ApplicationsGold and Silver Nanoparticles Synthesis and Applications