Litcius/Paper detail

Autoantibody mimicry of hormone action at the thyrotropin receptor

Bryan Faust, Christian B. Billesbølle, Carl‐Mikael Suomivuori, Isha Singh, Kaihua Zhang, Nicholas Hoppe, Antônio F. M. Pinto, Jolene K. Diedrich, Yagmur Muftuoglu, Mariusz W. Szkudlinski, Alan Saghatelian, Ron O. Dror, Yifan Cheng, Aashish Manglik

2022Nature58 citationsDOIOpen Access PDF

Topics & Concepts

Thyrotropin receptorExtracellularChemistryReceptorEGF-like domainTransmembrane domainCell biologyG protein-coupled receptorAutoantibodyHormone receptorBiophysicsBiochemistryGraves' diseaseBiologyInternal medicineEndocrinologyThyroidMedicineBinding domainBinding siteAntibodyImmunologyBreast cancerCancerGlycosylation and Glycoproteins ResearchThyroid Disorders and TreatmentsErythrocyte Function and Pathophysiology