Litcius/Paper detail

Potential methanol toxicity and the importance of using a standardised alcohol-based hand rub formulation in the era of COVID-19

Kate Dear, Lindsay Grayson, Rosemary Nixon

2020Antimicrobial Resistance and Infection Control41 citationsDOIOpen Access PDF

Abstract

OBJECTIVES: Hand sanitisers are urgently needed in the time of COVID-19, and as a result of shortages, some people have resorted to making their own formulations, including the repurposing of distilleries. We wish to highlight the importance of those producing hand sanitisers to avoid methylated spirits containing methanol and to follow WHO recommended formulations. METHODS: We explore and discuss reports of methanol toxicity through ingestion and transdermal absorption. We discuss the WHO formulations and explain the rationale behind the chosen ingredients. SHORT CONCLUSION: We advise those producing hand sanitisers to follow WHO recommended formulations, and advise those producing hand sanitisers using methylated spirits, to avoid formulations which contain methanol.

Topics & Concepts

Coronavirus disease 2019 (COVID-19)MedicineRepurposingEconomic shortageMethanolToxicityTransdermalPharmacologyChemistryOrganic chemistryPathologyEngineeringInternal medicineWaste managementDiseasePhilosophyGovernment (linguistics)LinguisticsInfectious disease (medical specialty)Poisoning and overdose treatmentsInfection Control and VentilationContact Dermatitis and Allergies