Litcius/Paper detail

Bottom-up computational design of shape-selective organic macrocycles for humid CO2 capture

Tao Liu, Hang Qu, Sam D Harding, Isaiah Borne, Linjiang Chen, John W. Ward, Simon C. Weston, Andrew I. Cooper

2025Nature Chemistry15 citationsDOIOpen Access PDF

Abstract

Abstract The capture of CO 2 emissions using porous solids is challenging because polar water molecules bind more strongly in most materials than non-polar CO 2 molecules. This is a challenge for both flue gas capture and for direct air capture alike. Here we develop a bottom-up computational screening workflow to calculate the binding energy of 27,446 diverse molecular fragments with both CO 2 and water. Most molecules favour water binding, but bent, clip-like aromatic molecules exhibit potential for the desired reverse selectivity. This suggests that aromatic macrocycles with specific shapes can promote multiple weak π – π interactions with CO 2 that surpass stronger but less numerous dipole– π interactions with water. We synthesize two water- and acid-stable molecular prisms with triangular and square geometries, as suggested by computation. Experiments confirm that the CO 2 capture capacity of these prisms is unaffected by high relative humidity, surpassing the performance of benchmark commercial porous materials.

Topics & Concepts

ChemistryMoleculeChemical polarityChemical physicsDipoleBent molecular geometryBinding energySelectivityComputational chemistryPolarNanotechnologyOrganic chemistryAtomic physicsMaterials scienceCatalysisAstronomyPhysicsMetal-Organic Frameworks: Synthesis and ApplicationsCarbon Dioxide Capture TechnologiesCovalent Organic Framework Applications