Screening and modification of (+)-germacrene A synthase for the production of the anti-tumor drug (−)-β-elemene in engineered Saccharomyces cerevisiae
Yuhan Hu, Qin Zhang, Xue Bai, Lianhui Men, Jing Ma, Dengyu Li, Mengdie Xu, Qiuhui Wei, Rong Chen, Daming Wang, Xiaopu Yin, Tianyuan Hu, Tian Xie
Topics & Concepts
Saccharomyces cerevisiaeChemistryDrugElemeneATP synthaseBiochemistryPharmacologyMicrobiologyEnzymeBiologyYeastApoptosisPlant biochemistry and biosynthesisMicrobial Metabolic Engineering and BioproductionPlant Gene Expression Analysis