Chrysin mitigated neuropathic pain and peripheral sensitization in knee osteoarthritis rats by repressing the RAGE/PI3K/AKT pathway regulated by HMGB1
Bo Xu, Yue Xu, Jian Kong, Yujiang Liu, Long Zhang, Fan Shen, Jiangping Wang, Xiaofeng Shen, Hua Chen, Hua Chen
Topics & Concepts
PI3K/AKT/mTOR pathwayProtein kinase BHMGB1ChrysinChemistryMedicinePharmacologyCancer researchEndocrinologyInternal medicineInflammationSignal transductionBiochemistryFlavonoidAntioxidantFlavonoids in Medical ResearchOsteoarthritis Treatment and MechanismsAdvanced Glycation End Products research