Thermosensitive and mucoadhesive in situ ocular gel for effective local delivery and antifungal activity of itraconazole nanocrystal in the treatment of fungal keratitis
Andi Dian Permana, Rifka Nurul Utami, Patricia Layadi, Achmad Himawan, Nana Juniarti, Qonita Kurnia Anjani, Emilia Utomo, Sandra Aulia Mardikasari, Andi Arjuna, Ryan F. Donnelly
Topics & Concepts
ItraconazolePoloxamerEx vivoIn vivoMaterials sciencePoloxamer 407Drug deliveryChemistryChromatographyPharmacologyPolymerIn vitroAntifungalMicrobiologyNanotechnologyMedicineBiochemistryBiologyBiotechnologyComposite materialCopolymerOcular Surface and Contact LensAdvanced Drug Delivery SystemsOcular Infections and Treatments