Isolation and Characterization of Three Pseudomonas aeruginosa Viruses with Therapeutic Potential
Xiao Wang, Jingjing Tang, Wen Dang, Zhen Xie, Fuhua Zhang, Xinwei Hao, Sihuai Sun, Xuan Liu, Yi Luo, Mengyuan Li, Yanchao Gu, Yao Wang, Qiwei Chen, Xihui Shen, Lei Xu
Abstract
Phage therapy is a promising therapeutic option for treating bacterial infections that do not respond to common antimicrobial treatments. Biofilm-mediated infections are particularly difficult to treat with traditional antibiotics, and the emergence of antibiotic-resistant strains has further complicated the situation. Pseudomonas aeruginosa is a bacterial pathogen that causes chronic infections and is highly resistant to many antibiotics.
Topics & Concepts
ORFSPhage therapyBiologyPseudomonas aeruginosaMicrobiologyMyoviridaeGenomeBacteriophageLytic cycleIsolation (microbiology)VirologyBacteriaOpen reading frameGeneticsVirusGeneEscherichia coliPeptide sequenceBacteriophages and microbial interactionsMicrobial infections and disease researchGenomics and Phylogenetic Studies