Atom-transfer radical addition of fluoroalkyl bromides to alkenes <i>via</i> a photoredox/copper catalytic system
Vladislav S. Kostromitin, Artem A. Zemtsov, Vladimir A. Kokorekin, Vitalij V. Levin, Alexander D. Dilman
Abstract
and N-heterocyclic carbene ligated copper bromide (IMesCuBr). The role of the iridium photocatalyst is to generate the fluoralkyl radical, while the copper promotes formation of the carbon-bromine bond.
Topics & Concepts
ChemistryAlkylCopperCatalysisPhotoredox catalysisAtom (system on chip)PhotochemistryFree-radical additionAtom-transfer radical-polymerizationPolymer chemistryMedicinal chemistryOrganic chemistryPhotocatalysisEmbedded systemComputer sciencePolymerCopolymerFluorine in Organic ChemistryRadical Photochemical ReactionsCatalytic C–H Functionalization Methods