High-throughput single-cell mass spectrometry enables metabolic network analysis by resolving phospholipid CC isomers
Simin Cheng, Chenxi Cao, Yao Qian, Huan Yao, Xiaoyun Gong, Xinhua Dai, Zheng Ouyang, Xiaoxiao Ma
Abstract
abundance profiling. Taken together, the developed method can be effectively used for in-depth structural lipid metabolism network analysis by high-throughput analysis of 142 MDA-MB-468 human breast cancer cells.
Topics & Concepts
Mass spectrometryPhospholipidChemistryLipidomicsThroughputSingle-cell analysisCellMetabolic pathwayMetabolomicsComputational biologyChromatographyBiochemistryMetabolismBiologyComputer scienceMembraneWirelessTelecommunicationsMetabolomics and Mass Spectrometry StudiesMass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications