Novel cytochrome P450 1 (CYP1) genes in tree shrews are expressed and encode functional drug-metabolizing enzymes
Yasuhiro Uno, Yutaro Noda, Norie Murayama, Kyoko Tsukiyama–Kohara, Hiroshi Yamazaki
Topics & Concepts
BiologyCYP1A2Cytochrome P450PseudogeneGeneCYP1B1Drug metabolismCYP2A6Molecular biologyBiochemistryGeneticsEnzymeGenomePharmacogenetics and Drug MetabolismDrug Transport and Resistance MechanismsDrug-Induced Hepatotoxicity and Protection