Litcius/Paper detail

First EZH2 Inhibitor Approved—for Rare Sarcoma

Unknown authors

2020Cancer Discovery53 citationsDOIOpen Access PDF

Abstract

The FDA has approved tazemetostat for treating epithelioid sarcoma. The drug produced responses in 15% of patients with the disease in a phase II trial, and 67% of the responses lasted at least 6 months. The drug is the first targeted treatment for epithelioid sarcoma.

Topics & Concepts

Epithelioid sarcomaMedicineSarcomaDrugInternal medicineOncologyCancer researchPharmacologyPathologySarcoma Diagnosis and TreatmentVascular Tumors and AngiosarcomasLymphoma Diagnosis and Treatment
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