Catalyst and Additive‐Free Selective Ring‐Opening Selenocyanation of Heterocycles with Elemental Selenium and TMSCN
Liguo Lu, Kang Bi, Xiaobo Huang, Miaochang Liu, Yunbing Zhou, Huayue Wu
Abstract
Abstract A catalyst and additive‐free strategy for selective ring‐opening selenocyanation of saturated heterocycles with elemental selenium and TMSCN is developed, affording a series of aliphatic selenocyanates and selenaheterocycles. In the case of unprotected unstrained N‐heterocycles, the reactions offer ammonium selenonitriles that prove to be an efficient selenonitrile reagent. magnified image
Topics & Concepts
ChemistryReagentSeleniumRing (chemistry)CatalysisOrganic chemistryElemental analysisAmmoniumCombinatorial chemistryOrganoselenium and organotellurium chemistrySulfur-Based Synthesis TechniquesCatalytic C–H Functionalization Methods