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A spatially resolved transcriptome landscape during thyroid cancer progression

Tian Liao, Yu Zeng, Weibo Xu, Xiao Shi, Cenkai Shen, Yuxin Du, Meng Zhang, Yan Zhang, Ling Li, Peipei Ding, Weiguo Hu, Zhiheng Huang, Man Him Matrix Fung, Qinghai Ji, Yu Wang, Shengli Li, Wenjun Wei

2025Cell Reports Medicine26 citationsDOIOpen Access PDF

Abstract

fibroblast abundance correlate with malignant progression and prognosis. These findings provide a spatially resolved framework of TME remodeling, offering insights for thyroid cancer diagnosis and treatment.

Topics & Concepts

TranscriptomeThyroid cancerComputational biologyCancerBiologyThyroidMedicineGeneticsGeneGene expressionSingle-cell and spatial transcriptomicsBioinformatics and Genomic NetworksFerroptosis and cancer prognosis
A spatially resolved transcriptome landscape during thyroid cancer progression | Litcius