Improved Dynamic Range of a Rhamnose-Inducible Promoter for Gene Expression in <i>Burkholderia</i> spp.
Andrew M. Hogan, Kevin R. Jeffers, Armando Palacios, Silvia T. Cardona
Abstract
Species of Burkholderia are dually recognized as being of attractive biotechnological potential but also opportunistic pathogens for immunocompromised individuals. Understanding the genotype-phenotype relationship is critical for synthetic biology approaches in Burkholderia to disentangle pathogenic from beneficial traits.
Topics & Concepts
BiologyBurkholderia cenocepaciaPromoterGeneGeneticsPlasmidBurkholderialac operonGene clusterMutantRegulation of gene expressionReporter geneGene expressionMolecular biologyBacteriaVirulenceCRISPR and Genetic EngineeringVibrio bacteria research studiesBacteriophages and microbial interactions