Collapse induration of alveoli is an ultrastructural finding in a COVID-19 patient
Matthias Ochs, Sara Timm, Sefer Elezkurtaj, David Horst, Jenny Meinhardt, Frank L. Heppner, Steffen Weber‐Carstens, Andreas C. Hocke, Martin Witzenrath
Abstract
<b>Electron microscopy reveals collapse induration with alveolar epithelial cell death, basal lamina denudation, collapse and sealing of alveoli in a COVID-19 patient, implicating surfactant dysfunction and alveolar instability in fibrosis initiation</b>https://bit.ly/38yEX2g
Topics & Concepts
Basal laminaUltrastructureCoronavirus disease 2019 (COVID-19)Electron microscopeFibrosisPathologyPulmonary surfactantMedicineChemistryDiseasePhysicsOpticsInfectious disease (medical specialty)BiochemistryNeonatal Respiratory Health ResearchInterstitial Lung Diseases and Idiopathic Pulmonary FibrosisRespiratory Support and Mechanisms