NLX-101, a highly selective 5-HT1A receptor biased agonist, mediates antidepressant-like activity in rats via prefrontal cortex 5-HT1A receptors
Ronan Depoortère, Agnès L. Auclair, Adrian Newman‐Tancredi
Topics & Concepts
5-HT1A receptorAgonistAntidepressantPrefrontal cortexSerotoninInternal medicineChemistry5-HT receptorReceptorAntagonistEndocrinology8-OH-DPATPsychologyBehavioural despair testReceptor antagonistPharmacologyNeuroscienceMedicineHippocampusCognitionNeurotransmitter Receptor Influence on BehaviorReceptor Mechanisms and SignalingNeuroscience and Neuropharmacology Research