Litcius/Paper detail

Targeting pan-essential genes in cancer: Challenges and opportunities

Liang Chang, Paloma Ruiz, Takahiro Ito, William R. Sellers

2021Cancer Cell198 citationsDOIOpen Access PDF

Topics & Concepts

LimitingDrug developmentTargeted therapyCancer therapyMedicineCancerGeneCancer treatmentDrugBiologyBioinformaticsComputational biologyPharmacologyGeneticsInternal medicineMechanical engineeringEngineeringProtein Degradation and InhibitorsUbiquitin and proteasome pathwaysCAR-T cell therapy research