Doxorubicin generates senescent microglia that exhibit altered proteomes, higher levels of cytokine secretion, and a decreased ability to internalize amyloid β
Luís Marques, Adiv A. Johnson, Alexandra Stolzing
Topics & Concepts
MicrogliaBiologyCell biologyDownregulation and upregulationSecretionSenescenceCytokineCellInflammationImmunologyEndocrinologyBiochemistryGeneNeuroinflammation and Neurodegeneration MechanismsTelomeres, Telomerase, and SenescenceNeutrophil, Myeloperoxidase and Oxidative Mechanisms