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The impact of false positive COVID-19 results in an area of low prevalence

Brendan Healy, Azizah Khan, Huria Metezai, Ian Blyth, Hibo Asad

2020Clinical Medicine135 citationsDOIOpen Access PDF

Abstract

False negative results in COVID-19 testing are well recognised and frequently discussed. False positive results, while less common and less frequently discussed, still have several adverse implications, including potential exposure of a non-infected person to the virus in a cohorted area. Although false positive results are proportionally greater in low prevalence settings, the consequences are significant at all times and potentially of greater significance in high-prevalence settings. We evaluated COVID-19 results in one area during a period of low prevalence. The consequences of these results are discussed and implications for these results in both high and low prevalence settings are considered. We also provide recommendations to minimise the risk and impact of false-positive results.

Topics & Concepts

MedicineCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)False Negative Reactions2019-20 coronavirus outbreakDemographyEnvironmental healthInternal medicinePathologyOutbreakDiseaseSociologyInfectious disease (medical specialty)SARS-CoV-2 detection and testingCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research
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