Blue-light induced iron-catalyzed chemoselective α-alkylation and α-olefination of arylacetonitriles with alcohols
Dingguo Song, Shiliang Wang, Weiwei Huang, Rong Chen, Fangyuan Hu, Lingxin Cheng, Xianghua Zhao, Fei Ling, Weihui Zhong
Abstract
This work describes the blue-light induced iron-catalyzed divergent synthesis of α-alkylated nitriles and α,β-substituted acrylonitriles from arylacetonitriles and alcohols at room temperature.
Topics & Concepts
ChemistryAlkylationCatalysisOrganic chemistryCombinatorial chemistryAsymmetric Hydrogenation and CatalysisCatalytic C–H Functionalization MethodsChemical Synthesis and Reactions