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Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors

Eman A. Fayed, Yousry A. Ammar, Marwa A. Saleh, Ashraf H. Bayoumi, Amany Belal, Ahmed B. M. Mehany, Ahmed Ragab

2021Journal of Molecular Structure63 citationsDOI

Topics & Concepts

ChemistryQuinoxalineIC50CytotoxicityApoptosisDocking (animal)Cell cultureStereochemistryMutantErlotinibIn vitroPharmacologyBiochemistryEpidermal growth factor receptorReceptorOrganic chemistryGeneBiologyMedicineNursingGeneticsSynthesis and Biological EvaluationCancer therapeutics and mechanismsSynthesis and biological activity
Design, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors | Litcius