Metabolic engineering generates a transgene-free safety switch for cell therapy
Volker Wiebking, James O. Patterson, Renata M. Martin, Monica Chanda, Ciaran M. Lee, Waracharee Srifa, Gang Bao, Matthew H. Porteus
Topics & Concepts
TransgeneInduced pluripotent stem cellBiologyGenetic enhancementTransplantationCell growthCell biologyCellCancer researchEmbryonic stem cellGeneticsGeneMedicineSurgeryCRISPR and Genetic EngineeringVirus-based gene therapy researchCAR-T cell therapy research