Withaferin A Induces Heat Shock Response and Ameliorates Disease Progression in a Mouse Model of Huntington’s Disease
Tripti Joshi, Vipendra Kumar, Еlena Kaznacheyeva, Nihar Ranjan Jana
Topics & Concepts
ProteostasisWithaferin AHuntingtinHuntington's diseaseWithania somniferaHuntingtin ProteinHSF1BiologyProtein aggregationCell biologyNeuroprotectionHeat shockMutantHeat shock proteinNeurodegenerationHsp70NeuroscienceBiochemistryMedicineInternal medicineDiseasePathologyGeneAlternative medicineGenetic Neurodegenerative DiseasesMitochondrial Function and PathologyHeat shock proteins research