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Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer

Andrew H. Ko, Alexander C. Jordan, Evan Tooker, Simon F. Lacey, Renee B. Chang, Yan Li, Alan P. Venook, Margaret A. Tempero, Lloyd E. Damon, Lawrence Fong, Mark H. O’Hara, Bruce L. Levine, J. Joseph Melenhorst, Gabriela Plesa, Carl H. June, Gregory L. Beatty

2020Molecular Therapy56 citationsDOIOpen Access PDF

Topics & Concepts

MesothelinChimeric antigen receptorPancreatic cancerCancer researchCD19AntigenReceptorMedicineImmunologyCancerInternal medicineImmunotherapyCAR-T cell therapy researchCancer Immunotherapy and BiomarkersSafe Handling of Antineoplastic Drugs
Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer | Litcius