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Bottom-up assembly of viral replication cycles

Oskar Staufer, Gösta Gantner, Ilia Platzman, Klaus Tanner, Imre Berger, Joachim P. Spatz

2022Nature Communications14 citationsDOIOpen Access PDF

Abstract

Bottom-up synthetic biology provides new means to understand living matter by constructing minimal life-like systems. This principle can also be applied to study infectious diseases. Here we summarize approaches and ethical considerations for the bottom-up assembly of viral replication cycles.

Topics & Concepts

Replication (statistics)Viral replicationComputational biologyBiologyComputer scienceVirologyVirusEvolution and Genetic DynamicsCRISPR and Genetic EngineeringGene Regulatory Network Analysis
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