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miR-485-5p/HSP90 axis blocks Akt1 phosphorylation to suppress osteosarcoma cell proliferation and migration via PI3K/AKT pathway

Qing Liu, Zhenting Wang, Xiaohua Zhou, Mingying Tang, Wei Tan, Tianshi Sun, Yi-Fang Wang, Youwen Deng

2020Journal of Physiology and Biochemistry59 citationsDOI

Topics & Concepts

Gene knockdownAKT1Protein kinase BPI3K/AKT/mTOR pathwayPhosphorylationCell growthCancer researchCell biologyDownregulation and upregulationSignal transductionBiologyChemistryMolecular biologyApoptosisBiochemistryGenePI3K/AKT/mTOR signaling in cancerHeat shock proteins researchRNA modifications and cancer
miR-485-5p/HSP90 axis blocks Akt1 phosphorylation to suppress osteosarcoma cell proliferation and migration via PI3K/AKT pathway | Litcius