Graphdiyne–hemin-mediated catalytic system for wound disinfection and accelerated wound healing
Arbab Ali, Jiaming Liu, Huige Zhou, Tao Liu, Muhammad Ovais, Huibiao Liu, Yukui Rui, Chunying Chen
Abstract
The well-dispersed and biosafe hemin/graphdiyne (GDY) nanocomposite (GDY–hemin) exhibits high peroxidase activity, which can decompose H<sub>2</sub>O<sub>2</sub> to generate highly-toxic hydroxyl radicals, leading to bacterial death in both <italic>in vitro</italic> and <italic>in vivo</italic>.
Topics & Concepts
HeminPeroxidaseWound healingIn vivoRadicalCatalysisIn vitroMaterials scienceChemistryEnzymeBiochemistryBiologyImmunologyHemeBiotechnologyGraphene and Nanomaterials ApplicationsCarbon and Quantum Dots ApplicationsNanoparticles: synthesis and applications