Challenges identifying efficacious miRNA therapeutics for cancer
Meirav Segal, Frank J. Slack
Abstract
MicroRNAs are a class of small non-coding RNAs (22–23 nucleotides), which regulate gene expression at the post-transcriptional level and play key roles in tumorigenesis and other diseases [1,2]. Mi...
Topics & Concepts
microRNACarcinogenesisBiologyComputational biologyGene expressionGeneCancerRegulation of gene expressionGeneticsBioinformaticsCancer researchMicroRNA in disease regulationRNA Interference and Gene DeliveryCircular RNAs in diseases