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Influenza Activity and Composition of the 2022–23 Influenza Vaccine — United States, 2021–22 Season

Angiezel Merced-Morales, P. Daly, Anwar Isa Abd Elal, Noreen Ajayi, Ekow Annan, Alicia Budd, John Barnes, Arielle Colón, Charisse N Cummings, A. Danielle Iuliano, Juliana DaSilva, Nick Dempster, Shikha Garg, Larisa V. Gubareva, D Hawkins, Amanda C. Howa, Stacy Huang, Marie K. Kirby, Krista Kniss, Rebecca Kondor, Jimma Liddell, Shunte Moon, Ha Nguyen, Alissa O’Halloran, Catherine Smith, Thomas Stark, Katie J. Tastad, Dawud Ujamaa, Dave E. Wentworth, Alicia M. Fry, Vivien G. Dugan, Lynnette Brammer

2022MMWR Morbidity and Mortality Weekly Report85 citationsDOIOpen Access PDF

Abstract

Before the emergence of SARS-CoV-2, the virus that causes COVID-19, influenza activity in the United States typically began to increase in the fall and peaked in February. During the 2021-22 season, influenza activity began to increase in November and remained elevated until mid-June, featuring two distinct waves, with A(H3N2) viruses predominating for the entire season. This report summarizes influenza activity during October 3, 2021-June 11, 2022, in the United States and describes the composition of the Northern Hemisphere 2022-23 influenza vaccine. Although influenza activity is decreasing and circulation during summer is typically low, remaining vigilant for influenza infections, performing testing for seasonal influenza viruses, and monitoring for novel influenza A virus infections are important. An outbreak of highly pathogenic avian influenza A(H5N1) is ongoing; health care providers and persons with exposure to sick or infected birds should remain vigilant for onset of symptoms consistent with influenza. Receiving a seasonal influenza vaccine each year remains the best way to protect against seasonal influenza and its potentially severe consequences.

Topics & Concepts

MedicineHuman mortality from H5N1Influenza A virus subtype H5N1OutbreakInfluenza vaccineLive attenuated influenza vaccineVaccinationInfluenza A virusVirusVirologyFlu seasonInfluenza seasonSeasonal influenzaPandemicOrthomyxoviridaeImmunologyEnvironmental healthCoronavirus disease 2019 (COVID-19)DiseaseInternal medicineInfectious disease (medical specialty)Influenza Virus Research StudiesViral Infections and VectorsRespiratory viral infections research