Advances in Stroke
Lorie Richards, Steven C. Cramer
Abstract
Stroke recovery therapies promote favorable neural plasticity, both during spontaneous recovery and the chronic phase. Activity-based therapies based on intense practice, some aided by integration of computers and telehealth, have shown promise. These studies emphasize key therapeutic variables such as dose, intensity, and timing. Preclinical drug studies have shown promise, but human translation has been challenged by identifying the target patient subgroup, requirements for concomitant training, and aligning biomarkers with preclinical evidence.
Topics & Concepts
MedicineStroke recoveryStroke (engine)NeuroplasticityConcomitantIntensive care medicinePhysical medicine and rehabilitationNeuroscienceInternal medicinePhysical therapyRehabilitationPsychiatryMechanical engineeringBiologyEngineeringStroke Rehabilitation and RecoveryAcute Ischemic Stroke ManagementNeurological Disorders and Treatments